Back to search

Article

Gene signature characteristic of elevated stromal infiltration and activation is associated with increased risk of hematogenous and lymphatic metastasis in serous ovarian cancer

2019-12-11

Abstract excerpt

<title>Abstract</title> <p>Background The clinical significance of hematogenous and lymphatic metastasis in ovarian cancer has been increasingly addressed, as it plays an imperative role in the formation of both intraperitoneal and distant metastases. Our objective is to identify the key molecules and biological processes potentially related to this relatively novel metastatic route in serous ovarian cancer.Meth...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
373b9eea-8b20-53ee-a099-30fa31e3b832
DOI
10.21203/rs.2.15974/v2
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Gene signature characteristic of elevated stromal infiltration and activation is associated with increased risk of hematogenous and lymphatic metastasis in serous ovarian cancerDOI 10.21203/rs.2.15974/v2
Analyzing the extracellular matrix-dominated immune landscape of high-grade serous ovarian cancer to determine prognosis and guide therapySemantic proximity
A Collagen-Remodeling Gene Signature Regulated by TGF-β Signaling Is Associated with Metastasis and Poor Survival in Serous Ovarian CancerSemantic proximity
Characterization of Candidate Factors Associated With the Metastasis and Progression of High Grade Serous Ovarian CancerSemantic proximity
UBE2J1 is identified as a novel plasma cell-related gene involved in the prognosis of high-grade serous ovarian cancerSemantic proximity
Integrated Bioinformatical Analysis for Identification the invasion-related Genes in ovarian cancerSemantic proximity
Subtype-specific analysis of gene co-expression networks and immune cell profiling reveals high grade serous ovarian cancer subtype linkage to variable immune microenvironmentSemantic proximity
Single-cell transcriptomic construction of fibroblast score for analysis of immune infiltration in primary and metastatic ovarian cancerSemantic proximity
Integrated analysis of spatial transcriptomics and CT phenotypes for unveiling the novel molecular characteristics of recurrent and non-recurrent high-grade serous ovarian cancerSemantic proximity
Single-Cell RNA Sequencing Reveals the Tissue Architecture in Human High-Grade Serous Ovarian CancerSemantic proximity
A Nine-Immune-Related Gene Prognostic Signature for Predicting Outcomes in High-Grade Serous Ovarian CancerSemantic proximity
High expression of Fibroblast activation protein (FAP) predicts poor outcome in high-grade serous ovarian cancerSemantic proximity
Single-cell analysis reveals the stromal dynamics and tumor-specific characteristics in the microenvironment of ovarian cancerSemantic proximity
Select a neighboring publication to make it the new centre.