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Phylogenomic framework and virulence gene boundaries of emerging Shiga toxin-producing <i>Escherichia coli</i> O118 informed by the comprehensive profiling of 359 O118 genomes

2025-05-01

Abstract excerpt

Non-O157 Shiga toxin-producing Escherichia coli (STEC), particularly the O118 serogroup, are emerging pathogens linked to severe foodborne illnesses, including hemolytic uremic syndrome. The hallmark of STEC virulence is the production of a potent phage-borne cytotoxin, often accompanied by the locus of enterocyte effacement (LEE). This study explores the genomic landscape, virulence factors, and resistance trait...

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Literature Corpus work
36e279dc-07ca-52f3-ace2-8e69c584544b
DOI
10.1101/2025.04.29.651274
Open publication

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Phylogenomic framework and virulence gene boundaries of emerging Shiga toxin-producing <i>Escherichia coli</i> O118 informed by the comprehensive profiling of 359 O118 genomesDOI 10.1101/2025.04.29.651274
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