Back to search

Article

Comprehensive Pathogen Profiling in Adult Patients with Severe Acute Respiratory Infections Using Metagenomic Next-Generation Sequencing of Sputum Samples

2025-12-15

Abstract excerpt

Severe Acute Respiratory Infection (SARI) remains a major global health burden, yet conventional diagnostics frequently fail to identify the causative pathogens. This study aimed to comprehensively characterize the respiratory microbial landscape in adult SARI and to evaluate the clinical utility of an optimized long-read metagenomic next-generation sequencing (mNGS) workflow. A total of 101 respiratory specimens...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
367d182e-cf2e-5c49-8c6a-633022862c24
DOI
10.64898/2025.12.12.25342137
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Comprehensive Pathogen Profiling in Adult Patients with Severe Acute Respiratory Infections Using Metagenomic Next-Generation Sequencing of Sputum SamplesDOI 10.64898/2025.12.12.25342137
Comprehensive Pathogen Profiling in Adult Patients with Severe Acute Respiratory Infections Using Metagenomic Next-Generation Sequencing of Sputum SamplesSemantic proximity
Sputum Respiratory Pathogen Genomic Surveillance: A Practical Approach for Long-Read Metagenomic SequencingSemantic proximity
Metagenomics Reveals Pathogenic Diversity and Temporal Dynamics in Severe Pneumonia Among Patients in Adult Intensive Care UnitSemantic proximity
Sputum Respiratory Pathogen Genomic Surveillance: A Practical Approach for Long-Read Metagenomic SequencingSemantic proximity
Metagenomic Sequencing Analysis of Respiratory Pathogens in the Jiangsu Region of China: A Multicenter Epidemiological Study (2025)Semantic proximity
Clinical application of metagenomic next-generation sequencing in etiologic diagnosis of severe pneumonia in adultsSemantic proximity
Metagenomic Next-generation Sequencing Indicates More Precise Pathogens in patients with pulmonary infection: a retrospective studySemantic proximity
Metagenomic next-generation sequencing Reveals Respiratory Pathogen distribution in COVID-19Semantic proximity
Clinical utility of metagenomic next-generation sequencing in pathogen detection for lower respiratory tract infectionsSemantic proximity
Respiratory Tract Pathogen Detection in Children: Clinical Practice and Considerations of mNGS and tNGS TechnologiesSemantic proximity
Improving Suspected Pulmonary Infection Diagnosis by Bronchoalveolar Lavage Fluid Metagenomic Next-Generation Sequencing: a Multicenter Retrospective StudySemantic proximity
Clinical Efficacy and Diagnostic Value of Metagenomic Next-Generation Sequencing (mNGS) in Hospital-Acquired Pneumonia: A Stratified Retrospective Study of Responders and Non- RespondersSemantic proximity
Select a neighboring publication to make it the new centre.