Back to search

Article

Association of extensive RNA disruption with natural killer cell-mediated death of K562 chronic myelogenous leukemia cells

2023-06-05

Abstract excerpt

Extensive degradation of tumour 28S and 18S ribosomal RNAs, coupled with the accumulation of ribosomal RNA degradation products, is associated with pathologic complete response and improved disease-free-survival in breast cancer patients. Various chemotherapy agents and cellular stressors are known to trigger this process, termed ‘RNA disruption’, in tumour cells. However, it’s unclear whether immunotherapies, wit...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
35dee797-56ae-55f1-8ba7-170d9a14b25e
DOI
10.21203/rs.3.rs-2944450/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 8 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Association of extensive RNA disruption with natural killer cell-mediated death of K562 chronic myelogenous leukemia cellsDOI 10.21203/rs.3.rs-2944450/v1
Self-Assembling Antisense Oligo-RNA Structures and M2-M1 Macrophage Phenotype Transformers for Cancer TreatmentSemantic proximity
Moderate degradation does not preclude microarray analysis of small amounts of RNA.Semantic proximity
Natural Killer Cell-Mediated Killing of Freshly Isolated Neuroblastoma CellsSemantic proximity
Optimizing NK-92 Serial Killers: Gamma Irradiation, CD95/FasLigation, And NK Or LAK Attack Limit Cytotoxic EfficacySemantic proximity
Expression of NK Cell Surface Receptors in Breast Cancer Tissue as Predictors of Resistance to Antineoplastic TreatmentSemantic proximity
Transcriptome sequencing of Hodgkin lymphoma Hodgkin and Reed-Sternberg cells reveals escape from NK cell recognition and an unfolded protein responseSemantic proximity
Necroptotic cell death in anti‐cancer therapySemantic proximity
Noncoding RNAs in pyroptosis and cancer progression: Effect, mechanism, and clinical applicationSemantic proximity
Select a neighboring publication to make it the new centre.