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Long Non-coding RNA PVT1 Promotes Chondrocyte Extracellular Matrix Degradation by Acting as a Sponge for miR-140 in IL-1β-stimulated Chondrocytes

2021-07-15

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<title>Abstract</title> <p><bold>Background:</bold> Osteoarthritis (OA) is a common degenerative joint disease, and chondrocyte extracellular matrix (ECM) degradation is one vital pathological feature of OA. Long noncoding RNA (lncRNA), a new kind of gene regulator, plays an important role in pathogenesis of many diseases like OA. Recent studies have confirmed that lncRNA plasmacytoma variant translocation 1 (PVT...

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Literature Corpus work: 3588ce74-ee28-5862-a184-079488dd05a8
DOI: 10.21203/rs.3.rs-708786/v1

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