Article

Spinal muscular atrophy is also a disorder of spermatogenesis

2024-11-20

Abstract excerpt

<title>Abstract</title> <p>Background Spinal muscular atrophy (SMA) patients benefit from pre-mRNA splicing modifiers targeting the <italic>SMN2</italic> gene, which aims to increase functional SMN production. The animal toxicity affecting spermatogenesis associated with one such treatment raised questions about male SMA patients’ spermatogenesis. Methods This descriptive, cross-sectional study was conducted fr...

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Literature Corpus work: 35809227-c371-564e-8907-1a46c719e5bb
DOI: 10.21203/rs.3.rs-4477947/v1

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