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Human Umbilical Cord Mesenchymal Stem Cell-derived Exosomal miR-27b Attenuate Subretinal Fibrosis via Suppressing Epithelial-mesenchymal Transition by Targeting HOXC6

2020-11-02

Abstract excerpt

<h4>Background: </h4> and aimSubretinal fibrosis resulting from neovascular age-related macular degeneration (nAMD) is one of the major causes of serious and irreversible vision loss worldwide, and no definite and effective treatment exists currently. Retinal pigmented epithelium (RPE) cells are crucial in maintaining the visual function of normal eyes and its epithelial–mesenchymal transition (EMT) is associated...

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Literature Corpus work
3560f13d-51b7-574a-b9e7-63c9c36d6473
DOI
10.21203/rs.3.rs-99751/v1
Open publication

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