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Proteomic Insight into the Role of Exosomes in Proliferative Vitreoretinopathy Development

11 May 2022

Abstract excerpt

Purpose: To characterize vitreous humor (VH) exosomes and to explore their role in the development of proliferative vitreoretinopathy (PVR) using mass spectrometry-based proteome profiling. Methods: Exosomes were isolated from undiluted VH from patients with retinal detachment (RD) with various stages of PVR (n = 9), macular hole (MH; n = 5), or epiretinal membrane (ERM; n = 5) using differential...

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PMID: 35628842
DOI: 10.3390/jcm11102716

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