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Machine learning-based single cell and integrative analysis reveals that baseline mDC predisposition predicts protective Hepatitis B vaccine response

2021-02-23

Abstract excerpt

Vaccination to prevent infectious disease is one of the most successful public health interventions ever developed. And yet, variability in individual vaccine effectiveness suggests a better mechanistic understanding of vaccine-induced immune responses could improve vaccine design and efficacy. We have previously shown that protective antibody levels could be elicited in a subset of recipients with only a single d...

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Literature Corpus work
354a5d58-7495-5856-becc-edc95d1826ee
DOI
10.1101/2021.02.22.21251864
Open publication

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Machine learning-based single cell and integrative analysis reveals that baseline mDC predisposition predicts protective Hepatitis B vaccine responseDOI 10.1101/2021.02.22.21251864
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