Article

SORCS2 Modifies Niemann–Pick Type C Cellular Phenotypes

2026-08-25

Abstract excerpt

<title>Abstract</title> <p> Niemann–Pick type C (NPC) disease, caused by pathogenic variants in <italic>NPC1</italic> or <italic>NPC2</italic> , is characterized by disrupted intracellular lipid trafficking and significant phenotypic heterogeneity. We previously established that genetically diverse <italic>Saccharomyces cerevisiae</italic> strains (West African, WA; Sake, SA; Wine European, WE; and North A...

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Identifiers and source

Literature Corpus work: 34ea62ba-376d-5d51-924a-3bb559d21797
DOI: 10.21203/rs.3.rs-10619258/v1

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