Article

Cutaneous Hyperpigmentation and Familial Gastrointestinal Stromal Tumor Associated with Germline KIT Mutation Treated with Imatinib

2020-10-21

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Familial gastrointestinal stromal tumor (GIST) has been identified with multiple GISTs containing the mutations in germline KIT and PDGFRA. There are only 35 kindreds with germline KIT and 6 with PDGFRA mutations have been reported so far. Familial GIST is often characterized by a series of manifestations, such as multiple lesions, hyperpigmentation, mastocytosi...

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Literature Corpus work: 346e9f52-657f-5daf-bd51-0c00295fba03
DOI: 10.21203/rs.3.rs-92093/v1

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