Article

Cutaneous Hyperpigmentation and Familial Gastrointestinal Stromal Tumor Associated With Germline KIT Mutation Treated With Imatinib: A Chinese Case Report

2020-10-07

Abstract excerpt

<title>Abstract</title> <p>BackgroundFamilial gastrointestinal stromal tumor (GIST) has been identified with multiple GISTs harboring the mutations in germline KIT and PDGFRA. There are only 35 kindreds with germline KIT and 6 with PDGFRA mutations have been reported to date. Familial GIST is often characterized by a series of manifestations, such as multiple lesions, hyperpigmentation, mastocytosis, and dysphagi...

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Literature Corpus work: 1f5b5c0f-afcc-5655-98e2-7da00e6c48ba
DOI: 10.21203/rs.3.rs-85318/v1

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