Association between Neuropathic Pain Characteristics and DNA Methylation of <em>TRPA1</em> in Human Peripheral Blood

Abstract excerpt

<h4>Background: </h4> Elucidation of epigenetic mechanisms correlating with neuropathic pain in humans is crucial for the prevention and treatment of this treatment-resistant pain state. In the present study, associations between neuropathic pain characteristics and DNA methylation of the transient receptor potential ankyrin 1(TRPA1) gene were evaluated in chronic pain patients and preoperative patients. <h4>Metho...

Topics

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• Epithelial Cells
• Histone Deacetylase Inhibitors Research
• Ion Channels and Receptors
• Mutation
• Neurons
• Pain
• Pain Management and Opioid Use
• Pain Mechanisms and Treatments

Identifiers and source

Literature Corpus work

343a1658-064b-596c-8633-5fe7f00f6e1a

DOI

10.20944/preprints201911.0101.v1