Article
The metabolic syndrome alters the miRNA signature of porcine adipose tissue‐derived mesenchymal stem cells
5 Jul 2017
Abstract excerpt
Autologous transplantation of mesenchymal stem cells (MSCs) is a viable option for the treatment of several diseases. Evidence indicates that MSCs release extracellular vesicles (EVs) and that EVs shuttle miRNAs to damaged parenchymal cells to activate an endogenous repair program. We hypothesize that comorbidities may interfere with the packaging of cargo in MSC-derived EVs. Therefore, we examined whether...
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