Article

Associations of RANKL/RANK/OPG pathway genetic variants and prosthodontic factors with severe residual ridge resorption

2026-08-25

Abstract excerpt

Severe residual ridge resorption (RRR) compromises prosthodontic success in edentulous patients, yet the underlying genetic mechanisms driving this alveolar bone loss remain undefined. Although genetic variants within the receptor activator of nuclear factor-κB ligand (RANKL)/receptor activator of nuclear factor-κB (RANK)/osteoprotegerin (OPG) axis drive osteoclast-mediated bone pathology, their specific role in R...

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Literature Corpus work: 334132f5-938e-5b77-9e7f-4e4c1349eee4
DOI: 10.1038/s41598-026-67688-3

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