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Article

Investigation of genetic polymorphisms associated with severe root resorption in orthodontic surgery patients.

Brazilian dental journal - 1 Jan 2026

Schröder Ângela Graciela Deliga, Kuczera Milena Sampaio, Araujo Cristiano Miranda de, Freitas Veridiana Pereira de Sá de, Meger Michelle Nascimento, Santos Katheleen Miranda Dos, Scariot Rafaela, Küchler Erika Calvano, Baratto-Filho Flares

Abstract excerpt

This study aimed to evaluate the association between genetic polymorphisms in the BMP2, BMP4, RUNX2, and SMAD6 genes and the presence of severe external apical root resorption (EARR) in orthodontic patients undergoing orthognathic surgery. EARR represents a significant adverse outcome in orthodontic treatments, and genetic susceptibility may influence its occurrence. A cross-sectional study was conducted with 158...

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Identifiers

PMID: 42385003
DOI: 10.1590/0103-644020266742
PMCID: PMC13313149

Genes

SMAD6
BMP2
BMP4
RUNX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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