Article

Safety and immunogenicity and efficacy of the self-amplifying mRNA ARCT-154 COVID-19 vaccine

2023-09-20

Abstract excerpt

<title>Abstract</title> <p>Combination of waning immunity and lower effectiveness of approved COVID-19 vaccines against SARS-CoV-2 variants necessitates new vaccines. We evaluated the safety, immunogenicity and efficacy of a novel self-amplifying mRNA COVID-19 vaccine against the D614G variant, ARCT-154, in an integrated phase 1/2/3a/3b, randomized, observer-blind trial in Vietnamese adults. Two doses of ARCT-154...

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Literature Corpus work: 32f76d5a-64f0-5efb-9c41-2416b8bdb307
DOI: 10.21203/rs.3.rs-3329097/v1

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