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Real-world effectiveness and non-inferiority evaluation and comparison of mRNA- and protein-based COVID-19 vaccines: a randomized study protocol (BEEHIVE)

2025-07-23

Abstract excerpt

<h4>Background</h4> Surveillance of COVID-19 vaccine effectiveness was extensive upon vaccine introduction; however, it slowed once pandemic status was withdrawn in May 2023. Continued monitoring of updated vaccine formulations is needed to ensure maintenance of vaccine effectiveness (VE) in the face of evolving viral strains. <h4>Objective</h4> The randomized, controlled BEEHIVE study ( NCT06065176 ) was develo...

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Literature Corpus work
c577abd1-d26f-5218-870b-2716f1e43699
DOI
10.1101/2025.07.21.25331726
Open publication

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Real-world effectiveness and non-inferiority evaluation and comparison of mRNA- and protein-based COVID-19 vaccines: a randomized study protocol (BEEHIVE)DOI 10.1101/2025.07.21.25331726
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