Article
A Mathematical Model of Glomerular Fibrosis in Diabetic Kidney Disease to Predict Therapeutic Efficacy
2023-04-04
Abstract excerpt
1 <h4>ABSTRACT</h4> <h4>Background</h4> Glomerular fibrosis is a tissue damage that occurs within the kidneys of chronic and diabetic kidney disease patients. Effective treatments are lacking, and the mechanism of glomerular damage reversal is poorly understood. <h4>Method</h4> A mathematical model suitable for hypothesis-driven systems pharmacology of glomerular fibrosis in diabetes was developed from a previo...
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Identifiers and source
- Literature Corpus work
- 32afa39c-bb80-51a2-b895-51f596f2bcee
- DOI
- 10.1101/2023.04.02.535270