Article

Epigenetic analysis on RUNX3 mislocalization and its association with tumor microenvironment alteration in non-small cell lung cancer

2023-09-18

Abstract excerpt

To investigate the epigenetic characteristics and tumor microenvironment status that might probably underlie RUNX3 mislocalization in NSCLC. Epigenetic markers, PD-L1 and CD3/8 were assessed in TMA and TCGA datasets. Methylation level at RUNX3 promoter was assessed via pyrosequencing. RNA-seq assays were performed. NSCLC patients’ survival with different patterns of RUNX3 expression was determined. Among NSCLC wit...

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Literature Corpus work: 327c5de6-6a51-55f5-bdc0-6118419b82c3
DOI: 10.21203/rs.3.rs-3327279/v1

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