Evolution and Transmission Dynamics of Wild Poliovirus in Pakistan and Afghanistan (2012-2023): implications for global polio eradication

Abstract excerpt

<title>Abstract</title> <p>Despite concerted global vaccination efforts, wild poliovirus remains endemic in two countries in 2024, Pakistan and Afghanistan. This study uses phylogeographic analysis of poliovirus genetic and epidemiological data from clinical and wastewater surveillance to identify the causes of poliovirus persistence and routes of spread over the last decade (2012 to 2023). Poliovirus genetic div...

Topics

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• Animal Disease Management and Epidemiology
• Genotype
• Molecular Epidemiology
• Pakistan
• Phylogeny
• Poliovirus
• Viral gastroenteritis research and epidemiology
• Viral Infections and Immunology Research

Identifiers and source

Literature Corpus work

3277a942-b744-5556-a11f-77b392038b8c

DOI

10.21203/rs.3.rs-5331855/v1