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Evolution and transmission dynamics of wild poliovirus in Pakistan and Afghanistan (2012-2023)

4 Jun 2025

Abstract excerpt

Despite concerted global vaccination efforts, wild poliovirus remains endemic in two countries in 2024, Pakistan and Afghanistan. This study uses phylogeographic analysis of poliovirus genetic and epidemiological data from clinical and wastewater surveillance to identify the causes of poliovirus persistence and routes of spread over the last decade (2012 to 2023). Poliovirus genetic diversity declined after 2020,...

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PMID: 40467546
DOI: 10.1038/s41467-025-60432-x

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