Article

Genetic Basis of Familial Cancer Risk: A Narrative Review

2025-11-27

Abstract excerpt

Familial cancers are caused by inherited mutations in specific genes that regulate cell growth, division, and repair. Approximately 5–10% of all cancer cases have a hereditary component, where germline mutations in certain genes increase an individual’s susceptibility to developing cancer. Two major categories of genes are involved in cancer development: tumour suppressor genes and oncogenes. Both play critical ro...

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Literature Corpus work: 31c2b070-7d59-5d62-a730-3c58c335cd53
DOI: 10.20944/preprints202511.2088.v1

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