Article
Network Pharmacognosy of <i>Galphimia glauca</i> : Mapping the Molecular Landscape of a Traditional Mexican Medicinal Plant
2025-01-03
Abstract excerpt
This study explores the pharmacological landscape of Galphimia glauca , a traditional Mexican medicinal plant known for its sedative and anti-inflammatory effects. Using network pharmacognosy, we analyzed the interactions of G. glauca ’s bioactive compounds, Galphimines A-I, with human protein targets. SwissTargetPrediction identified 214 unique protein targets across the galphimines, revealing a core-periphery...
Topics
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- Bioinformatics and Genomic Networks
- Computational Drug Discovery Methods
- Genomics, phytochemicals, and oxidative stress
- Inflammatory mediators and NSAID effects
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Lung Cancer Treatments and Mutations
- Pharmacological Effects of Natural Compounds
- Rheumatoid Arthritis Research and Therapies
Identifiers and source
- Literature Corpus work
- 316577fe-e16d-5c67-80f3-c03f4e05174c
- DOI
- 10.1101/2025.01.02.631171
