Article

Downregulation of B3GNT6 Predicts Poor Outcome in Colorectal Cancer Patients

2020-12-29

Abstract excerpt

<h4>Background: </h4> B3GNT6 encodes the core 3 synthase in O-glycan biosynthesis. It is commonly expressed in the GI tract, while its clinical significance in colorectal cancer remains largely unknown. <h4>Methods: </h4> We gathered mRNA transcriptomic sequencing data from 3 Gene Expression Omnibus (GEO) datasets (GSE37182, GSE39582, GSE103512) and The Cancer Genome Atlas (TCGA) to compare the B3GNT6 mRNA level b...

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Literature Corpus work: 30e4c38f-78b9-5910-8041-612471bae5af
DOI: 10.21203/rs.3.rs-127044/v1

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