Article

Lynch syndrome: influence of additional susceptibility variants on cancer risk

2022-10-20

Abstract excerpt

<title>Abstract</title> <p>Some patients with Lynch syndrome (LS) have extreme phenotypes, i.e. cancer before the recommended screening age, or cancer for which there are no screening guidelines. We made the hypothesis that additional germline variants in cancer susceptibility genes (CSG) could explain some of these phenotypes. We compared the prevalence of additional CSG variants in LS patients with a cancer dia...

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Literature Corpus work: 3082e3db-c1ab-5da0-8dbd-a9d2b9d1f3fe
DOI: 10.21203/rs.3.rs-2159229/v1

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