Article

The abundance of harmful homozygous rare variants in children of consanguineous parents

2023-07-19

Abstract excerpt

<title>Abstract</title> <p>Here we show that the individuals born of the union between double first cousins (paternal <italic>and</italic> maternal) had 20 times more deleterious homozygous rare Single Nucleotide Variants (SNVs) than those who had unrelated parents. Furthermore, the children of first cousins had ten times, and the children of second cousins had two times more of these SNVs compared to those prese...

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Literature Corpus work: 30563aee-ec8f-52cc-8be7-2ec1c702f598
DOI: 10.21203/rs.3.rs-3169355/v1

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