Article

Transposable element landscape in <i>Drosophila</i> populations selected for longevity

2019-12-06

Abstract excerpt

<h4>ABSTRACT</h4> Transposable elements (TEs) inflict numerous negative effects on health and fitness as they replicate by integrating into new regions of the host genome. Even though organisms employ powerful mechanisms to demobilize TEs, transposons gradually lose repression during aging. The rising TE activity causes genomic instability and was implicated in age-dependent neurodegenerative diseases, inflammati...

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Literature Corpus work: 2f8c152c-c211-5b94-aad4-725a72a6872d
DOI: 10.1101/867838

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