Article

Screening of terpenoids as potential therapeutics against Zaire ebolavirus infection through pharmacophore-based drug design

2019-07-10

Abstract excerpt

Backgroud: Ebola virus disease (EVD) has spread to various countries in the world and has caused many deaths. Five different virus species can cause EVD, but the most virulent is Zaire ebolavirus (EBOV). The genome of EBOV includes seven genes that encode proteins playing essential roles in the virus lifecycle. Among these proteins, VP24 plays a vital role in the inhibition of the host cells’ immune system. There...

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Literature Corpus work: 2f888c99-2a48-5d4c-a892-f52bbce88044
DOI: 10.12688/f1000research.19238.1

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