Article

Rapid and Reproducible Multimodal Biological Foundation Model Development with AIDO.ModelGenerator

2025-07-04

Abstract excerpt

Foundation models (FMs) for DNA, RNA, proteins, cells, and tissues have begun to close long-standing performance gaps in biological prediction tasks, yet each modality is usually studied in isolation. Bridging them requires software that can ingest heterogeneous data, apply large pre-trained backbones from various sources, and perform multimodal benchmarking studies at scale. We present AIDO.ModelGenerator, an ope...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2f7a58c4-8425-5568-ba29-1d765083510d
DOI: 10.1101/2025.06.30.662437

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Rapid and Reproducible Multimodal Biological Foundation Model Development with AIDO.ModelGeneratorDOI 10.1101/2025.06.30.662437Read

Tahoe-x1: Scaling Perturbation-Trained Single-Cell Foundation Models to 3 Billion ParametersSemantic proximity Read

HoloCell: A Generative Foundation Model for Holistic Cellular ModelingSemantic proximity Read

DeepSeq: High-Throughput Single-Cell RNA Sequencing Data Labeling via Web Search-Augmented Agentic Generative AI Foundation ModelsSemantic proximity Read

Genome modeling and design across all domains of life with Evo 2Semantic proximity Read

CellFM: a large-scale foundation model pre-trained on transcriptomics of 100 million human cellsSemantic proximity Read

AetherCell: A generative engine for virtual cell perturbation and <i>in vivo</i> drug discoverySemantic proximity Read

Scaling Dense Representations for Single Cell with Transcriptome-Scale ContextSemantic proximity Read

Large Scale Foundation Model on Single-cell TranscriptomicsSemantic proximity Read

AENetMoX: Fast and Precise scRNA-seq Gene Regulatory Network Inference Through Multi-Modal Feature Integration in Brain OrganoidsSemantic proximity Read

GeneCompass: Deciphering Universal Gene Regulatory Mechanisms with Knowledge-Informed Cross-Species Foundation ModelSemantic proximity Read

Breaking Through Biology's Data Wall: Expanding the Known Tree of Life by Over 10x using a Global Biodiscovery PipelineSemantic proximity Read

EpiAgent: Foundation model for single-cell epigenomic dataSemantic proximity Read