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A Bayesian spatial random effects model characterisation of tumour heterogeneity implemented using Markov chain Monte Carlo (MCMC) simulation

2016-08-26

Abstract excerpt

The focus of this study is the development of a statistical modelling procedure for characterising intra-tumour heterogeneity, motivated by recent clinical literature indicating that a variety of tumours exhibit a considerable degree of genetic spatial variability. A formal spatial statistical model has been developed and used to characterise the structural heterogeneity of a number of supratentorial primitive neu...

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Literature Corpus work
2f674edb-7cf6-514e-be79-dc5f104a85c3
DOI
10.12688/f1000research.9355.1
Open publication

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A Bayesian spatial random effects model characterisation of tumour heterogeneity implemented using Markov chain Monte Carlo (MCMC) simulationDOI 10.12688/f1000research.9355.1
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