Article

Assessment of Changes in Genetic Transcriptome in Nasal Epithelial Cells Exposed to Black Carbon and Pollen Allergen by High-throughput Transcriptomics

2020-12-04

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Evidence suggests that air pollution may be associated with an increase in airway responsiveness to allergens, an increase in bioavailability of airborne allergens and possibly exacerbation of allergic rhinitis (AR). Environmental black carbon (BC) is an important constituent of atmospheric particulate matter (PM), for which the mechanisms underlying its effects...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2f07df83-5adb-56ee-977e-919818559d20
DOI: 10.21203/rs.3.rs-118284/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Assessment of Changes in Genetic Transcriptome in Nasal Epithelial Cells Exposed to Black Carbon and Pollen Allergen by High-throughput TranscriptomicsDOI 10.21203/rs.3.rs-118284/v1Read

Consistent Biomarkers and Related Pathogenesis Underlying Asthma Revealed by Systems Biology ApproachSemantic proximity Read

Application of biclustering of gene expression data and gene set enrichment analysis methods to identify potentially disease causing nanomaterialsSemantic proximity Read

Development of an inhaled endotoxin challenge protocol for characterizing evoked cell surface phenotype and genomic responses of airway cells in allergic individuals.Semantic proximity Read

Genetic Effects of Welding Fumes on the Development of Respiratory System DiseasesSemantic proximity Read

Disease-specific differences in particulate matter handling drive pathogenic responses in human derived nasal epithelial cellsSemantic proximity Read

Carbon nanoparticles adversely affect CFTR expression and toxicologically relevant pathwaysSemantic proximity Read

The genes and the environment in nasal allergySemantic proximity Read

Unique transcriptomic responses of rat and human alveolar macrophages in an in vitro model of overload with TiO2 and carbon blackSemantic proximity Read

Transcriptome-wide profiling discover: PM2.5 aggravates airway dysfunction through epithelial barrier damage regulated by Stanniocalcin 2 in an OVA-induced modelSemantic proximity Read

Systematic Analysis of Multiwalled Carbon Nanotube-Induced Cellular Signaling and Gene Expression in Human Small Airway Epithelial CellsSemantic proximity Read

Woodsmoke and Diesel Exhaust: Distinct Transcriptomic Profiles in the Human Airway EpitheliumSemantic proximity Read

Club cell secretory protein 16 up-regulates cell proliferation, inhibits inflammation and pyroptosis against particular matter 2.5 -induced epithelium damage in asthmatic miceSemantic proximity Read