Article

Late diagnosis of Marfan syndrome is associated with unplanned aortic surgery and cardiovascular death

2024-04-23

Abstract excerpt

<h4>Background</h4> Marfan syndrome (MFS) guidelines recommend optimal pharmacological therapy (OPT) and replacement of the ascending aorta (RAA) at 5.0cm diameters to prevent acute type A aortic dissection (ATAAD) and death. The effect of early MFS diagnosis and initiation of therapy on outcomes is not known. <h4>Objective</h4> To evaluate the effect of age at MFS diagnosis and therapy initiation on delayed RAA a...

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Literature Corpus work: 2ed45b93-25cb-558f-9f33-22ee7f67a0fd
DOI: 10.1101/2024.04.22.24305998

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