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Analysis of serum and plasma identifies differences in molecular coverage, measurement variability, and candidate biomarker selection

29 May 2012

Abstract excerpt

PURPOSE: To compare the use of serum and plasma in multiplex immunoassay analyses of 190 proteins and small molecules, and associated molecular pathways. We also tested whether differences between these biofluids can influence the identification of potential biomarkers in a preliminary study comparing bipolar disorder patients with controls. EXPERIMENTAL DESIGN: Using multiplexed immunoassay analyses, we compared...

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PMID: 22641612
DOI: 10.1002/prca.201100061

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