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Realigning Clinical Studies from HG38 to T2T-CHM13 to Discover Differences Between Using Different Reference Genomes

2025-10-23

Abstract excerpt

<title>Abstract</title> <p>In genomics research, reference genomes are used by researchers to compare sequencing data. Human reference genomes represent the complete set of DNA within a cell. The first human reference genome was released in 2003, though incomplete due to technological barriers. In December of 2013, the HG38 genome, an updated version of previous genomes, was released, and it currently remains the...

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Literature Corpus work: 2e20e932-06c5-5054-a74e-8b3cd6f94551
DOI: 10.21203/rs.3.rs-7643242/v2

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