Article

Frontier Large Language Models for Comprehensive Medication Review in CKD Patients with Polypharmacy: A Trap-Embedded Synthetic Benchmark

2026-05-26

Abstract excerpt

<h4>Background</h4> Patients with CKD and polypharmacy face high rates of drug-related problems, yet comprehensive medication review remains time-intensive and inconsistently performed. Large language models (LLMs) may augment this process, but existing benchmarks use multiple-choice formats that do not reflect open-ended, nephrology-specific review. We developed a trap-embedded synthetic CKD benchmark and evalua...

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Literature Corpus work: 2e095cec-1981-53ab-8e89-f84ee170a625
DOI: 10.64898/2026.05.23.26353939

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