Article

Oncogene alterations in primary, recurrent, and metastatic human bone tumors

1996-10-01

Abstract excerpt

We investigated the structure and the expression of various oncogenes in three of the most common human bone tumors—osteosarcoma (36 samples from 34 patients), giant cell tumor (10 patients), and chondrosarcoma (18 patients)—in an attempt to identify the genetic alterations associated with these malignancies. Alterations of RB and p53 were detected only in osteosarcomas. Alterations of c-myc, N-myc, and c-fos were...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2df98ed6-3f0c-56f8-a87c-9e404dcd0ec1
DOI: 10.1002/(sici)1097-4644(199610)63:1<37::aid-jcb3>3.0.co;2-0

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Oncogene alterations in primary, recurrent, and metastatic human bone tumorsDOI 10.1002/(sici)1097-4644(199610)63:1<37::aid-jcb3>3.0.co;2-0Read

Oncogene alterations in primary, recurrent, and metastatic human bone tumors.Semantic proximity Read

Secondary malignant giant-cell tumour of bone: molecular abnormalities of p53 and H-ras gene correlated with malignant transformation.Semantic proximity Read

Understanding the Osteosarcoma Pathobiology: A Comparative Oncology ApproachSemantic proximity Read

Genetic imbalances revealed by comparative genomic hybridization in osteosarcomasSemantic proximity Read

Etiology of OsteosarcomaSemantic proximity Read

Primary pulmonary osteosarcoma: case report and molecular analysis.Semantic proximity Read

A case of secondary malignant giant-cell tumor of bone with p53 mutation after long-term follow-up.Semantic proximity Read

Biology of osteogenic sarcoma.Semantic proximity Read

A new subtype of high-grade mandibular osteosarcoma with RASAL1/MDM2 amplification.Semantic proximity Read

Giant cell-rich osteosarcoma of the vertebra with murine double minute chromosome 2- and cyclin-dependent kinase 4-positive and histone H3F3A mutant p.Gly34Trp-negative immunophenotypes.Semantic proximity Read

H3F3A G34 mutation DNA sequencing and G34W immunohistochemistry analysis in 366 cases of giant cell tumors of bone and other bone tumors.Semantic proximity Read

Primary versus radiation-associated craniofacial osteosarcoma: Biologic and clinicopathologic comparisons.Semantic proximity Read