Article

Gene therapy for hemophilia B in immature mice using ScAAV-DJ/8-LP1-hFIXco vector

2023-10-13

Abstract excerpt

<title>Abstract</title> <p>Hemophilia B is an X-linked bleeding disorder that derives from the mutation in the gene encoding coagulation factor IX(FIX). Gene therapy provided the promising hope to cure the disease. Currently, pure virus injection is exclusively limited to adults, resulting in favorable outcomes. However, this approach has rarely been tested in pediatric patients due to its considerable impact on...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2d4c1803-43cd-5c3a-93c1-41e841c3310b
DOI: 10.21203/rs.3.rs-3379986/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Gene therapy for hemophilia B in immature mice using ScAAV-DJ/8-LP1-hFIXco vectorDOI 10.21203/rs.3.rs-3379986/v1Read

Human Umbilical Cord Mesenchymal Stem Cell-Based Gene Therapy for Hemophilia B using scAAV-DJ/8-LP1-hFIXco TransductionSemantic proximity Read

Hemophilia gene therapy comes of ageSemantic proximity Read

Hemophilia gene therapy comes of ageSemantic proximity Read

Recent Advances in Gene Therapy for Hemophilia: Projecting the PerspectivesSemantic proximity Read

Gene Therapy: Paving New Roads in the Treatment of HemophiliaSemantic proximity Read

Hemophilia Gene Therapy: Ready for Prime Time?Semantic proximity Read

Activated Factor X delivered by Adeno-Associated virus significantly inhibited bleeding and alleviated hemophilia A/B arthropathy in hemophilia miceSemantic proximity Read

Gene Therapy for Inherited Bleeding DisordersSemantic proximity Read

Past, present and future of haemophilia gene therapy: From vectors and transgenes to known and unknown outcomesSemantic proximity Read

Recent Progress in Gene Therapy for HemophiliaSemantic proximity Read

Hemophilia A gene therapy: current and next-generation approachesSemantic proximity Read

Gene therapy for hemophiliaSemantic proximity Read