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Inhibitory Knowledge Flow from E-Communities of Practice Stabilizes Causal Gene Circuit Architectures in Single-Cell Foundation Models

2026-04-18

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Abstract Title: Inhibitory Knowledge Flow from E-Communities of Practice Stabilizes Causal Gene Circuit Architectures in Single-Cell Foundation Models <h4>Background: </h4> Single-cell foundation models (scFMs) are transforming gene regulatory network (GRN) inference, yet two fundamental challenges remain: (1) causal circuit architectures—particularly inhibitory dominance patterns—vary unpredictably across organs,...

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Literature Corpus work: 2d0e4ab2-a5a1-5717-843c-9b7f32745c74
DOI: 10.14293/pr2199.003418.v1

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