Article

Droplet microfluidics-based detection of very rare antibiotic-resistant subpopulation in clinical isolates of<i>Escherichia coli</i>from bloodstream infections

2025-03-10

Abstract excerpt

Population heterogeneity in bacterial phenotypes, such as antibiotic resistance, is increasingly recognized as a medical concern. Heteroresistance (HR) occurs when a predominantly susceptible bacterial population harbors a rare resistant subpopulation. During antibiotic exposure, these resistant bacteria can be selected and lead to treatment failure. Standard antibiotic susceptibility testing (AST) methods often f...

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Literature Corpus work: 2b952489-059c-5b3b-97be-f30ed8b29595
DOI: 10.1101/2025.03.05.25323409

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