Article

Rab11a mediates cell-cell spread and reassortment of influenza A virus genomes via tunneling nanotubes

2021-01-20

Abstract excerpt

Influenza A virus (IAV) genomes comprise eight negative strand RNAs packaged into virions in the form of viral ribonucleoproteins (vRNPs). Rab11a plays a crucial role in the transport of vRNPs from the nucleus to the plasma membrane via microtubules, allowing assembly and virus production. Here, we identify a novel function for Rab11a in the inter-cellular transport of IAV vRNPs using tunneling nanotubes (TNTs) as...

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Literature Corpus work: 2b055b6b-4ce4-5a8c-9e87-dedb317193e8
DOI: 10.1101/2021.01.20.427426

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