Article

SARS Vaccine Development

2005-07-01

Abstract excerpt

Developing effective and safe vaccines is urgently needed to prevent infection by severe acute respiratory syndrome (SARS)–associated coronavirus (SARS-CoV). The inactivated SARS-CoV vaccine may be the first one available for clinical use because it is easy to generate; however, safety is the main concern. The spike (S) protein of SARS-CoV is the major inducer of neutralizing antibodies, and the receptor-binding d...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2a9cf17c-3843-5eab-a867-55dfe1dc1b1f
DOI: 10.3201/eid1107.050219

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

SARS Vaccine DevelopmentDOI 10.3201/eid1107.050219Read

SARS Vaccine DevelopmentSemantic proximity Read

Receptor-binding domain as a target for developing SARS vaccines.Semantic proximity Read

SARS-CoV-2 Vaccines Based on the Spike Glycoprotein and Implications of New Viral Variants.Semantic proximity Read

Identification and characterization of novel neutralizing epitopes in the receptor-binding domain of SARS-CoV spike protein: Revealing the critical antigenic determinants in inactivated SARS-CoV vaccineSemantic proximity Read

Antibodies and Vaccines Target RBD of SARS-CoV-2Semantic proximity Read

Development of a Recombinant RBD Subunit Vaccine for SARS-CoV-2Semantic proximity Read

Cellular and humoral immunogenicity of a candidate DNA Vaccine Expressing SARS-CoV-2 Spike Subunit 1Semantic proximity Read

Potent and persistent antibody responses against the receptor-binding domain of SARS-CoV spike protein in recovered patientsSemantic proximity Read

SARS-CoV-2 mRNA vaccine requires signal peptide to induce antibody responsesSemantic proximity Read

Antigenic and Immunogenic Characterization of Recombinant Baculovirus-Expressed Severe Acute Respiratory Syndrome Coronavirus Spike Protein: Implication for Vaccine DesignSemantic proximity Read

Preclinical Study of DNA Vaccines Targeting SARS-CoV-2Semantic proximity Read

Immunogenicity and Protection Efficacy of Monomeric and Trimeric Recombinant SARS Coronavirus Spike Protein Subunit Vaccine CandidatesSemantic proximity Read