Article
Genetic relationship between Hashimoto`s thyroiditis and papillary thyroid carcinoma with coexisting Hashimoto`s thyroiditis.
PloS one - 1 Jan 2020
Subhi Ohoud, Schulten Hans-Juergen, Bagatian Nadia, Al-Dayini Roa'a, Karim Sajjad, Bakhashab Sherin, Alotibi Reem, Al-Ahmadi Alaa, Ata Manar, Elaimi Aisha, Al-Muhayawi Saad, Mansouri Majid, Al-Ghamdi Khalid, Hamour Osman Abdel, Jamal Awatif, Al-Maghrabi Jaudah, Al-Qahtani Mohammed Hussain
Abstract excerpt
Hashimoto's thyroiditis (HT) is present in the background of around 30% of papillary thyroid carcinomas (PTCs). The genetic predisposition effect of this autoimmune condition is not thoroughly understood. We analyzed the microarray expression profiles of 13 HT, eight PTCs with (w/) coexisting HT, six PTCs without (w/o) coexisting HT, six micro PTCs (mPTCs), and three normal thyroid (TN) samples. Based on a false...
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