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Antagonist actions of CMK-1/CaMKI and TAX-6/Calcineurin along the <i>C. elegans</i> thermal avoidance circuit orchestrate adaptation of nociceptive response to repeated stimuli

2024-09-19

Abstract excerpt

Response decrease following repeated exposure to innocuous or noxious stimuli is a conserved adaptation phenomenon often referred to as habituation. Impaired nociceptive habituation is associated with several pain conditions in human, but the underpinning molecular mechanisms are only partially understood. In the nematode Caenorhabditis elegans , thermo-nociceptive adaptation to repeated stimuli was previously sh...

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Literature Corpus work
2a20c13d-8f7b-59f2-b4e5-96c3ea8d90b7
DOI
10.1101/2024.09.18.613419
Open publication

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Antagonist actions of CMK-1/CaMKI and TAX-6/Calcineurin along the <i>C. elegans</i> thermal avoidance circuit orchestrate adaptation of nociceptive response to repeated stimuliDOI 10.1101/2024.09.18.613419
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