Article

INTESTINAL GLUCONEOGENESIS IS DOWNREGULATED IN PAEDIATRIC PATIENTS WITH COELIAC DISEASE

2021-09-14

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Untreated coeliac disease (CD) patients have increased levels of blood glutamine and a lower duodenal expression of glutaminase (GLS). Intestinal gluconeogenesis (IGN) is a process through which glutamine is turned into glucose in the small intestine, for which GLS is crucial. Animal studies suggest impaired IGN may have long-term effects on metabolic control and be associated...

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Literature Corpus work: 2a024f1b-8ddb-526f-bb91-45569ee427c6
DOI: 10.1101/2021.09.08.21262795

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