Article

DNA methylation as a potential mediator of the association between indoor air pollution and neurodevelopmental delay in a South African birth cohort

2022-05-20

Abstract excerpt

<h4>Background: </h4> Exposure to indoor air pollution during pregnancy has been linked to neurodevelopmental delay in toddlers. Epigenetic modification, particularly DNA methylation (DNAm), may explain this link. In this study, we employed three high-dimensional mediation analysis methods (HIMA, DACT, and gHMA) followed by causal mediation analysis to identify differentially methylated CpG sites and genes that me...

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Literature Corpus work: 296cab0f-8e45-5f17-b1ce-aa2b25c77caf
DOI: 10.21203/rs.3.rs-1670046/v1

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