Article

Characterisation of a novel genetically engineered mouse model of non-small cell lung cancer with a dynamic immune response

2021-01-01

Abstract excerpt

Lung cancer is the most common form of cancer in the world, both in terms of diagnosis and number of deaths per annum. Approximately 85% of cases diagnosed are non-small cell lung cancer (NSCLC), of which adenocarcinoma is the most common histological subtype. Specific DNA mutations allow for molecular characterisation of the disease and activating mutations in KRAS are present in one third of cases. The oncogene...

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Literature Corpus work: 2958ce27-f8bb-5170-a3f7-4f69227d4980
DOI: 10.5525/gla.thesis.82097

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