Article
Progress and applications of mouse models for human lung cancer.
The European respiratory journal - 1 Feb 2010
de Seranno S, Meuwissen R
Abstract excerpt
The continued progress of modelling lung cancer in mice has led not only to new means of understanding the molecular pathways governing human lung cancer, but it has also created a vast reservoir of alternative tools to test treatments against this malignancy. More sophisticated somatic mouse models for nonsmall cell lung cancer, small cell lung cancer and pulmonary squamous cell carcinoma have been generated...
Topics
- Alleles
- Animals
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Squamous Cell
- Disease Models, Animal
- Disease Progression
- Humans
- Lung Neoplasms
- Medical Oncology
- Mice
- Mice, Transgenic
- Models, Genetic
- Small Cell Lung Carcinoma
- Stem Cells
