Article

Zanubrutinib Attenuated Bleomycin-Induced Pulmonary Fibrosis by Inhibiting the TGF-β1 Signaling Pathway

2021-07-27

Abstract excerpt

<h4>Background: </h4> Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and fatal interstitial lung disease with high mortality and limited treatment. So far, the only drugs approved for the treatment of IPF are Nintedanib and Pirfenidone. Zanubrutinib, a BTK small molecule inhibitor, is approved for the treatment of mantle cell lymphoma (MCL) and chronic lymphocytic leukemia (CLL)/small lymphocytic ly...

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Literature Corpus work: 2907e9c1-2424-5c3d-b16b-9627964c98b6
DOI: 10.21203/rs.3.rs-720040/v1

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