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Article

RNAseq studies reveal distinct transcriptional response to vitamin A deficiency in small intestine versus colon, uncovering novel vitamin A-regulated genes

2019-10-13

Abstract excerpt

Vitamin A (VA) deficiency remains prevalent in resource limited countries, affecting over 250 million preschool aged children. Vitamin A deficiency is associated with reduced intestinal barrier function and increased risk of mortality due to mucosal infection. Using Citrobacter rodentium ( C. rodentium ) infection in mice as a model for diarrheal diseases in humans, previous reports showed reduced pathogen clear...

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Literature Corpus work
28f103da-cf12-5027-89fa-37c6d33f523f
DOI
10.1101/798504
Open publication

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RNAseq studies reveal distinct transcriptional response to vitamin A deficiency in small intestine versus colon, uncovering novel vitamin A-regulated genesDOI 10.1101/798504
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